Spermine Tetrahydrochloride

Spermine Tetrahydrochloride

Details
Form:Powder
Packaging :Drum, Aluminum Foil Bag
Specification:98%
Type:Nootropic
CAS No:306-67-2
Place of origin:Shaanxi China
MOQ:100g
Delivery lead time:About 3-5 days after payment confirmed
Category
Chemical Raw Materials
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Description
Technical Parameters

Products Description

 
 

Spermine Tetrahydrochloride is a naturally occurring bioactive biogenic polyamine compound. It is widely distributed in plant tissues, microorganisms and mammalian organisms, serving as an essential active substance in biological metabolism and a vital biochemical raw material for biological scientific research, biomedicine and bioengineering fields. Adopting high-quality biologically purified raw materials instead of traditional crude chemical synthesis processes, our Spermine Tetrahydrochloride is refined through advanced procedures including hydrochloric acid modification, multi-stage recrystallization, precision filtration, low-temperature drying and sterile screening, which ensures strict raw material control and zero impurity residue throughout the production process. The core active ingredient is high-purity spermine tetrahydrochloride, with a stable purity of over 98% tested by GC, exceeding universal industrial standards. The product presents as uniform white to off-white crystalline powder with no peculiar smell and no caking, featuring extremely stable physical and chemical properties. It owns excellent water solubility, dissolving completely and rapidly in pure water at room temperature, and is slightly soluble in ethanol, suitable for various aqueous solution experiments and production systems. Supported by a comprehensive quality inspection system, we strictly control key indicators such as loss on drying, residue on ignition, heavy metals and microorganisms, delivering products with high purity and ultra-low impurities that fully meet molecular biology grade standards. With outstanding stability under sealed storage at room temperature, the product is resistant to oxidation and decomposition, with tiny batch differences and high repeatability.

Function Analysis

Specification

 

Product Name

Spermine Tetrahydrochloride

Appearance

White or off-white crystalline powder

CAS No

306-67-2

Purity

98%

Density

1.01 g/mL at 20 °C

Molecular formula

C10H30Cl4N4

Molecular weight

334.157

Flash point

175.6ºC

Exact mass

332.106812

PSA

76.1

Storage

Cool and Dry Place

Shelf Life

24 months

COA

 

Items

Standards

Results

Appearance

White or off-white crystalline powder

Complies

Identification

By IR

Complies

By HPLC

Complies

Solubility

Slightly soluble in water, freely soluble in ethanol and acetone, soluble in 2-propanol and insoluble in heptane

Complies

Water Content

≤0.50%

0.22%

Residue on Ignition

≤0.20%

0.15%

Melting Point

120ºC~130ºC

121.0ºC~122.0ºC

Polymorphic Identity

XRD

Form 6

Heavy Metal

≤20ppm

Complies

Residue Solvent

Acetone: ≤5000ppm

ND

Toluene: ≤890ppm

137.7ppm

Dichloromethane: ≤600ppm

255.1ppm

Tetrahydrofuran: ≤720ppm

345.4ppm

ter-Butylmethylether: ≤5000ppm

ND

Related Substances

Any Single Impurity ≤0.10%

0.04%

Total Impurities: ≤0.50%

0.08%

Particle Size Distribution

D90: ≤ 45µm

Complies

Assay

98.0~101.5%

99.30%

Reference Standard

In-house Standard

Conclusion

The product complied to In-house standard.

Function

 

Stabilize genetic structure: Possesses excellent biological activity and physicochemical regulatory capacity, effectively stabilizing DNA molecular structure, resisting damage caused by external oxidative factors, protecting the integrity of biological macromolecules within organisms and cells, and maintaining genomic stability.

Neural Care and Regulation: Can modulate neuronal-related activity in the body, regulate neuronal enzyme activity, effectively improve neuronal condition, and provide stable neuroprotective effects.

Regulate platelet activity: precisely modulate the physiological state of platelets, inhibit abnormal platelet activation, and stabilize the physiological functions of blood cells.

Regulating cellular metabolism and growth: actively participating in intracellular metabolic processes and gene expression, appropriately controlling the pace of cell proliferation and differentiation, and effectively preventing excessive cell growth.

Antioxidant and anti-stress: Effectively eliminates excess free radicals in the body, alleviates oxidative stress responses, and reduces the negative impact of oxidative damage on cells and tissues.

Optimizing chromatin conformation: capable of regulating intracellular chromatin structure, ensuring normal physiological states of chromosomes, and supporting the stable functioning of biological genetic systems.

    Application   

 

Molecular Biology Experiments: Widely applied in DNA fragment precipitation under low-salt conditions, DNA separation via pulse field gel electrophoresis, chromosome extraction, and chromatin aggregation experiments.

Biomedical Research: Suitable for the detection of various tumor tissue specimens, including tissue flow cytometry analysis, cell cycle detection, and DNA content determination of biological tissues.

Bioanalytical Detection: Used as a professional auxiliary matrix material for glycan mass spectrometry detection experiments to optimize experimental and testing conditions.

Cell Culture Industry: Served as a standard additive for various cell culture media, supporting the experimental and large-scale cultivation of different cell lines.

Advanced Scientific R&D: Routinely adopted in basic neuroscience research, biomedical intermediate synthesis, and new drug development projects.

Plant Biotechnology: Applied as a core raw material for plant cell cultivation, plant biological characteristic research and related technical development.

 Shipment

     

 

product-2646-2646
product-2646-2646
product-2646-2646

 Package

     
product-1323-1323
product-1323-1323
product-1323-1323
product-1323-1323

 Payment

    
product-992-567
product-992-567
product-992-567

 

 

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