Products Description

Tianeptine Sulphate is an atypical tricyclic compound, presented as tianeptine hemisulfate monohydrate, which offers more stable chemical properties and better water solubility compared to the parent compound. Manufactured via rigorous chemical synthesis processes, our product undergoes multiple reactions including acylation, cyclization, and sulfonation, followed by purification steps such as recrystallization and column chromatography to ensure a purity of ≥99% (pharmaceutical grade) with impurity levels well below industry standards.

Tianeptine Sulphate appears as a white to off-white crystalline powder with no odor, soluble in water and methanol - characteristics that provide excellent applicability in formulation development. Our production adheres to GMP guidelines, and each batch undergoes comprehensive testing including HPLC, UV, and IR to guarantee consistent quality and reliability, meeting the stringent requirements of pharmaceutical R&D and laboratory research.

Specification

Product Name	Tianeptine Sulphate
Appearance	White to off-white crystalline powder
Purity	99%
CAS No	1224690-84-9
Molecular Formula	C₂₁H₂₅ClN₂O₄S·½H₂SO₄·H₂O
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

COA

Tests	Results	Specifications
Description	Off-white powder,very hygroscopic.	White to off-white crystalline powder,very hygroscopic.
Solubility	Complies	Freetly soluble In water and menol and
Identification	Complies	(1)By IR, To match with working standard
Identification	Complies	(2)It gives reaction of sodium
Impurities A	Not detected	≤0.1%
Related compounds	<0.1%	Any impurity ≤0.1%
Related compounds	0.19%	Total impurities ≤0.4%
Residual Solvents	Not detected	Acetidin ≤ 0.5%
	0.04%	Dichloe≤ 0.06%
	0.01%	Meanol≤ 0.3%
	0.01%
	Not detected	Ace≤0.041%
	0.01%	Ethanol≤0.5%
	Not detected	N, N-dimethylformamide ≤0.088%
Water	2.35%	≤ 5.0%
Assay	99.35%	99.0%-101.0%(On anhydrous basis)

Function

Core Central Nervous System Regulation: Core effects are antidepressant and anxiolytic, which can regulate brain neurotransmitter balance, improve core symptoms including low mood, anhedonia, generalized anxiety and panic attacks, with mild action and no obvious sedative side effects.

Dual Neuro & Cognitive Protection: Can promote hippocampal neurogenesis and dendritic growth, reverse stress-induced brain structural damage, and protect nerve cells from oxidative stress injury; meanwhile, it can improve memory, attention and mental agility, and relieve cognitive impairment associated with depression.

Multi-system Auxiliary Regulation: Can alleviate intestinal discomfort symptoms such as abdominal pain and bloating related to irritable bowel syndrome; meanwhile, it can reduce airway inflammatory response and provide auxiliary improvement for respiratory diseases such as asthma.

Application

· Pharmaceutical R&D & Industrial Production: Serves as a core intermediate for the research, formula development and large-scale production of new antidepressant and anxiolytic central nervous system drugs

· Laboratory Scientific Research: Used for basic research in neuroscience, pharmacology and toxicology, and can be used as a standard/reference substance for experiments including drug activity screening, mechanism of action exploration, and safety evaluation

· Formulation Development & Analytical Testing: Can be used to prepare various pharmaceutical dosage forms such as tablets, capsules and oral solutions; meanwhile, it can be used as a reference substance to complete qualitative and quantitative analysis and testing of related compounds