Products Description

The chemical full name of HBT1 (YDL223C) is 2-(2-(5-methyl-3-(trifluoromethyl)-1H-pyrazole-1-yl)acetylamino)-4,5,6,7-tetrahydrobenz[b]thiophene-3-carboxamide, which is a highly selective AMPA receptor enhancer. Its core value lies in enhancing the activity of AMPA receptors in a glutamate-dependent manner, while inducing the production of brain-derived neurotrophic factor, with almost no intrinsic agonistic effect. This unique mode of action makes it play an important role in neuroscientific research and potential therapeutic applications.HBT1 (YDL223C) is a white powder with no obvious agglomeration phenomenon, almost no obvious odor. This is a distinctive feature that distinguishes it from many neuroactive compounds. Its water solubility is poor, but it is easily soluble in polar organic solvents such as DMSO, methanol, and ethanol.

Specification

Product Name	HBT1
Other name	YDL233C
CasNo	48948-02-8
Content	0.98
MW:	386.39
MF:	C16H17F3N4O2S
Appearance	White powder

COA

Item	Specification	Result
Appearance	White powder	Conforms
Specification	99%	Conforms
Odor	Characteristic	Conforms
Particle size	100% pass 80 mesh	Conforms
Heavy metals
Total Heavy metals	≤10ppm	Conforms
Microbial
Total microbacterial count	≤1000cfu/g	Conforms
Yeast &Mould	≤100cfu/g	Conforms
Escherichia Coli presence	Negative	Conforms
Salmonella	Negative	Conforms
Staphylococcus	Negative	Conforms
Conclusion	Conforming to Enterprise Standard

Packing description:	Sealed export grade drum & double of sealed plastic bag
Storage:	Store in cool & dry place not freeze, keep away from strong light and heat
Shelf life:	2 years when properly stored

Function

It gently activates AMPA receptors by leveraging glutamate dependency, without forcibly overstimulating nerve cells. It exerts its regulatory effects only when glutamate is naturally released during physiological activities, thereby optimizing the efficiency of neural signal transmission and improving the smoothness of synaptic conduction.

YDL223C stably upregulates the expression of BDNF (brain-derived neurotrophic factor), nourishing brain synapses, maintaining neuronal activity, supporting improved neural metabolic status, and repairing minor nerve damage-making it suitable for research and development in brain health care.

The molecular structure of YDL223C is stable, resistant to acid and alkali, compatible with standard experimental systems, and less prone to oxidation or degradation during storage.

Application

YDL223C is widely used in cellular and animal experiments related to synaptic plasticity, neural development, and mechanisms of learning and memory. It is commonly employed by research institutions to establish models of neural injury for studying neurodegenerative mechanisms, making it a premium, essential compound in neuroscience laboratories.

As a functional intermediate raw material, YDL223C is utilized in the development of dietary formulations aimed at brain health maintenance and enhanced focus. Thanks to its mild and non-irritating properties, it is well-suited for formulation and research in brain health nutraceuticals and dietary supplements.