Products Description
PRL-8-53 raw powder is a nootropic research compound first synthesized in the 1970's by Dr Nikolaus Hansl while working at Creighton University,he single study involving humans showed PRL-8-53 improved word recollection scores both 24 and 96 hours after initial memorization. The mechanism of action of PRL-8-53 raw powder mainly revolves around the three major neurotransmitter systems, with the cholinergic system as the core, while simultaneously regulating the dopaminergic and serotonergic systems to achieve memory enhancement. Its core action is on the cholinergic system, which can enhance acetylcholine release and activate α7 nicotinic receptors, directly improving the encoding and retrieval processes of memory. At the same time, it can gently promote dopamine release, effectively improving the body's motivation and attention without triggering peripheral sympathetic excitation or affecting blood pressure and heart rate. In addition, it can also mildly inhibit serotonin release, balancing the ratio of dopamine to serotonin, thereby playing an auxiliary role in antidepressant and mood improvement.

Specification
|
Product name |
PRL-8-53 raw powder |
|
CAS No. |
51352-87-5 |
|
Purity |
99% |
|
Appearance |
White or almost white powder |
|
Package |
Aluminum Bag or Drum |
|
Storage |
Store in a closed container in a cool and dry place, below 5ºC. |
|
Retest Date |
2 years |
COA
|
ITEM |
SPECIFICATION |
RESULT |
METHOD |
|
Appearance |
White powder, neutral odor, highly hygroscopic |
Conforms |
Visual |
|
Identification |
Standard solution and test solution same spot,RF |
Conforms |
TLC |
|
Specific Optical |
-2.4°~ -2.8° |
-2.72° |
|
|
Heavy metals (as PB) |
≤10ppm |
Conforms |
AAS |
|
Sulfate (SO4) |
≤0.02% |
Conforms |
Colorimetry |
|
Chloride (Cl) |
≤0.02% |
Conforms |
Colorimetry |
|
Phosphate Ion (P) |
≤5ppm |
Conforms |
Colorimetry |
|
Residual solvent(ethanol) |
≤1.0% |
Conforms |
HS-GC |
|
pH |
4.5~7.0 |
5.10 |
|
|
Related substance |
Spot not bigger than standard solution spot |
No spot |
TLC |
|
Water Content |
≤2% |
0.26% |
KF |
|
Assay (dried basis) |
98.0%--102.0% |
99.48% |
Potentiometric titration |
|
Assay (dried basis) |
98.5%--100% |
99.2% |
HPLC |
Function
Enhances the acquisition and long-term retention of verbal information
Improves the speed of information acquisition and assists in establishing new memory connections
Regulates the signaling pathways of acetylcholine, dopamine and serotonin
Application
Cognitive neuroscience research
Pharmaceutical intermediate development
Age-related cognitive decline research
Educational and learning science research
Animal model applications
Shipment



Package




Payment



Hot Tags: prl-8-53 raw powder, China prl-8-53 raw powder manufacturers

