Products Description
Pentapeptide-18 powder is an artificially synthesized biomimetic pentapeptide. Its core structure is modified from the naturally occurring leucine enkephalin in the human body and is recognized as a mild neuro-regulating anti-wrinkle active ingredient in the current cosmetic compliance system. Unlike ordinary moisturizing and repairing peptides, its core mechanism of action is the neural-muscular regulation mechanism. By mimicking the effect of human enkephalin, it gently blocks excessive signal transmission between the skin's nerves and muscles, reduces acetylcholine release, and soothes frequent facial muscle contractions, addressing dynamic expression lines at their source. Pentapeptide-18 powder is a white powder, with a fine and uniform powder texture. It has no odor on its own, only carrying a very faint raw material flavor. After dilution, it is completely odorless. Pentapeptide-18 powder has excellent water solubility, which is one of its core advantages of strong adaptability. It can be quickly and completely dissolved in a normal temperature pure water system. After dissolution, the solution is clear, transparent, without sediment, and no suspended matter.

Specification
|
Product name |
Pentapeptide-18 |
|
CAS No. |
64963-01-5 |
|
Purity |
99% |
|
Appearance |
Powder |
|
Application |
Healthcare and skin care products |
|
Package |
Aluminum Bag or Drum |
|
Storage |
Store in a closed container in a cool and dry place, below 5ºC. |
|
Retest Date |
2 years |
COA
|
ITEM |
STANDARD |
RESULTS |
|
Appearance |
White Powder |
Complies |
|
Identification |
Retention time matches reference standard |
Complies |
|
Assay |
90.0%-105.0% |
99.63% |
|
Water Content (KF) |
≤5.0% |
0.13% |
|
Residue on Ignition |
≤0.5% (w/w) |
0.23% |
|
Heavy Metals |
≤10 ppm |
0.73ppm |
|
Acetate Content |
≤5.0% (w/w) |
0.29% |
|
Microbial Limits |
Total Aerobic Count: <1000 CFU/g |
<100 CFU/g |
|
Microbial Limits |
Yeast & Moulds: <100 CFU/g |
<10 CFU/g |
|
Microbial Limits |
E.Coli Negative |
Negative |
|
Microbial Limits |
Salmonella Negative |
Negative |
|
Conclusion |
Conform with enterprise specification.(Based on USP, EP, ChP) |
|
Function
Precisely improves dynamic wrinkles and blocks the root cause of wrinkle formation. Different from the shortcoming of ordinary moisturizing peptides that can only provide surface moisture, Pentapeptide-18 can gently regulate the nerve-muscle signal transmission of the skin, reduce the frequent contraction of facial muscles, and specifically target and improve wrinkles such as crow's feet, forehead wrinkles, and glabella wrinkles.
Pentapeptide-18 can effectively activate the activity of skin collagen and elastic fibers, promote the regeneration of collagen in the dermis layer, and replenish the lost elastic nutrients of the skin. Long-term use can improve problems such as skin relaxation and sagging, rough texture, and dryness caused by aging, staying up late, and ultraviolet damage. It can effectively enhance facial firmness and skin transparency, making mature skin and early aging skin states more delicate and tight.
Pentapeptide-18 is not merely a single anti-aging ingredient; it also possesses excellent skin repair capabilities. In the formula, it can assist in strengthening the skin barrier, alleviating external environmental irritation, seasonal sensitivity, and skin discomfort caused by medical aesthetic minimally invasive procedures.
Application
Pentapeptide-18 is the core essential ingredient of the anti-aging and mature skin care line. It can be directly applied to mainstream skincare products such as anti-aging essence, toner, and moisturizing repair gel. The formula has a high adaptability and does not affect the original texture, color and smell of the products. It can easily create gentle and highly effective anti-aging products.
The in-hospital medical beauty repair series products are widely used as exclusive products for overseas medical beauty clinics, including post-operative repair essence, minimally invasive soothing kits, in-hospital firming repair lotion, and skin stability serum, etc.
In line with the global trend of minimalist and additive-free skincare, it can be used in special anti-aging products for sensitive skin, skincare series suitable for pregnant women, and minimalist effective skincare products without fragrance or alcohol.
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