Products Description

Coluracetam just might be the next new nootropic to dominate the market of brain supplements in the coming years. Like many of the other most popular nootropics, Coluracetam is a Racetam compound derived from Piracetam. Coluracetam has a lot of characteristics in common with other Racetams, but there are also some important distinctions.Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.

Specification

Product Name	Coluracetam
CAS No	135463-81-9
Molecular formula	C19H23N3O3
Molecular weight	341.404
Grade	Pharmaceutical Grade
Color	White crystalline powder
Purity	99%
Shelf Life	2 years

COA

Items	Standards	Results	Method
Appearance	White crystalline fine powder	Conforms	Visual
Sulfate	≤0.05%	0.06%	USP
Odor	Characteristic	Conforms	Organoleptic
Heavy metals	≤10ppm	Conforms	AAS
Melting point	194ºC-202ºC	196.4ºC-198.4ºC	USP
Residue on Ignition	≤0.1%	0.05%	75ºC/5hrs
Related subtances	≤0.5%	0.34%	HPLC
Loss on drying	≤0.5%	0.26%	105ºC/3hrs
Ph value	2.3-2.7	2.47	USP
Iron	<60ppm	Conforms	AAS
Lead	<1ppm	Conforms	AAS
Casmium	<1ppm	Conforms	AAS
E.coli	Negative	Conforms	CP2005
Yeast & Mold	<100cfu/g	25cfu/g	CP2005
Salmonella	Negative	Conforms	CP2005
Total plate count	<1000cfu/g	80cfu/g	CP2005
Assay phenibut	≥99.0%	99.31%	HPLC

Function

1. Cognitive Regulation

It regulates the synthesis and metabolism of brain cholinergic neurotransmitters, optimizes the efficiency of brain information transmission, positively regulates working memory and spatial memory, improves the operating state of brain nerves, relieves low state caused by mental fatigue, and maintains efficient brain operation.

2. Neuroprotective Effect

It antagonizes excitotoxic damage of neurons, repairs the metabolic environment of damaged nerve cells, maintains the stability of the blood-brain barrier, reduces damage to central nerves and optic nerve cells caused by external stimuli and ischemic environment, and reduces the probability of neuronal degeneration.

3. Emotional Homeostasis Regulation

It assists in balancing mood-related neurotransmitters such as dopamine and serotonin in the brain, improves emotional imbalance caused by long-term pressure, relieves nervous tension, and maintains emotional stability.

Application

- Scientific Research: Applied in neuroscience related experiments, cholinergic nerve pathway model construction, neuronal cell culture experiments and pharmacological model building of new neural compounds. It is also suitable for comparative experiments of neural compounds, drug target mechanism research and academic research data collection.

- Dietary Supplement Raw Materials: Serves as a compliant raw material for formulating brain health dietary supplements, customized compound nutrition formulas and adult brain care products. It is applicable to functional food formula debugging, compound production and mass feeding of high-end nutritional supplements.

- Pharmaceutical R&D Intermediates: Used as a lead compound for new neural drug research and development, pre-development of psychiatric drugs and formula screening of central nervous system drugs. It supports pre-synthesis of pharmaceutical APIs and sample preparation for pre-clinical trials of new drugs.

- Pet Health Raw Materials: Applied in formula research and development of elderly pet care products and raw material addition of pet functional nutrition products, suitable for formula debugging and mass production of new pet health products.

- Fine Chemical Ingredients: Used for proportioning high-end biochemical products